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BioProcessing Fittings - PharmaLok Clamps

The biopharmaceutical industry has made a strong move towards single-use technology, so Nordson MEDICAL has developed ground-breaking clamp designs that simplify the assembly process by making it effortless to securely attach sanitary fittings to bag ports and filters.

Nordson MEDICAL’s PharmaLok™ clamps are ASME BPE compliant and operate at a maximum pressure of 80 psi. Single-use and easy-open clamp sizes include .5” to .75“ and 1” to 1.5“, and the tube clamp supports tubing sizes from .5” to 1.25“.

Pharmalok clamps provide a significant advancement for the industry, as a number of existing solutions either require tools for closure or consist of multiple components, which turns what should be a simple operation into a difficult and awkward process.

"As a founding member of BPSA, Nordson MEDICAL has been fortunate enough to have insight into the needs of the biopharm industry,” comments Ken Davis, Global Marketing Manager for Nordson MEDICAL. “User-friendly solutions are increasingly demanded, and single-use systems have developed into an overwhelming market trend. Incorporating these factors into the PharmaLok™ has resulted in an ideal solution for our customers."

Easily operated with one hand, PharmaLok’s Patent pending design allows effortless attachment of fittings to bag ports and filters. The user simply rests the fitting in the PharmaLok’s regulation-sized slot, lightly grips the surrounding handles, and listens for the sound of clicks to confirm a secure connection.

Single-Use Clamps & Easy-Open Clamps Features & Benefits

  • ASME BPE 2014 DT-9.3.1 compliant
  • DIN compliant
  • Easy to use, one-handed closure - no tools needed
  • Tamper evident
  • Zip tie compatible
  • 360° compression
  • Connects both plastic and stainless steel fittings
  • SIP/CIP compatible

Tube Clamp Features & Benefits

  • Designed for use with silicone and TPE tubing
  • Operating pressure up to 150 psi


  • Materials:
    • USP Class VI & ISO 11137 certified glass-filled nylon
  • Sterilization:
    • Gamma Radiation up to 50 kGy
    • Autoclavable up to 273°F (134°C) for a maximum of 30 min.
  • Single-Use & Easy-Open Clamp Sizes:
    • .5" to .75" and 1" to 1.5"
  • Tube Clamp Size:
    • .5" to 1.25"
  • Operating Temperature:
    • -94°F (-70°C) to 140°F (60°C)
  • Maximum Pressure:
    • 80 psi (conforms to ASME BPE-2014 PM-4.2.2)


PharmaLok™ Tube Clamp Compatibility

Silicone and TPE Tubing
Tubing ID Tubing OD
  5/8" 3/4" 7/8" 1" 1-1/8" 1-1/4" 1-1/2"
1/2" No Yes NA NA NA NA NA
5/8" NA No Yes Yes NA NA NA
3/4" NA NA NA Yes Yes NA NA
1" NA NA NA NA NA Yes Yes


Reinforced Silicone and Reinforced TPE Tubing
Tubing ID Tubing OD
  7/8" 1" 1-1/8" 1-1/4" 1-3/8"
1/2" Yes NA NA NA NA
5/8" NA Yes NA NA NA
3/4" NA NA Yes NA NA
7/8" NA NA NA Yes NA
1" NA NA NA NA Yes